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 What is the delta plus variable

What is the delta plus variable?



Delta Plus variant:




    Delta plus (AY.1) is another mutation of the well-known “delta” variant (B.1.617.2) and according to the researchers, Delta Plus contains the K417N mutation in the spike protein.



    The known coronary delta variant from which it is also transmitted is highly contagious and potentially more dangerous than the current prevalent variants.



    Indian health officials said the variant showed increased transmissibility, stronger binding to lung cell receptors and a possible decrease in response to monoclonal antibodies.



    India has the second highest number of coronavirus cases in the world, with nearly 30 million cases and 389,302 deaths reported.



    India has classified a new type of coronavirus first identified in Europe as a 'cause for concern' and, according to the BBC, the mutation changes from 'cause for concern' to 'cause for concern' when it provides evidence of at least one of several criteria.  Include mild transmission, more severe disease, lower neutralizing antibodies or lower treatment efficacy and vaccines.




    India's health ministry says research has shown that the so-called Delta Plus variant - also known as AY.1 - spreads more easily, binds more easily to lung cells and is potentially resistant to monoclonal antibody treatment.



    This variant is related to deltas, the current species of concern that was first identified in India last year and is believed to have caused a second wave of fatal infections this summer.






    The health ministry said the Delta Plus variant, which was first detected in India in April, was detected in 22 samples from six districts in three states - Maharashtra, Kerala and Madhya Pradesh.  It is one of the countries hardest hit by the epidemic.





    The Delta Plus variant is also found in 9 other countries: USA, Great Britain, Portugal, Switzerland, Japan, Poland, Nepal, Russia and China - compared to the highly infectious original Delta strain that has now spread to 80 countries.





    Viruses change all the time, and most changes don't make sense, according to the report.  Some even harm the virus, but others can make the disease more contagious or dangerous, and these mutations tend to take hold.





    However, leading virologists have questioned the classification of Delta Plus as a variant of concern, saying that there is still no data showing that the variant was more contagious or resulted in more serious illness compared to the other variants.



    "There are no data yet to support the theory of 22-sequence differentiation," said Dr Jagandeep Kang, a virologist and the first Indian woman elected as a member of the Royal Society of London.  Consider if this is a really annoying variable.  "





    This means that India needs more data to determine whether the variant has been neutralized by antibodies from available vaccines or infected with another type of coronavirus.





    Comprehensive data on the increase in infection, diagnostic failure of routine tests that do not capture the variant and whether the variant causes more serious disease are also needed.



    "We need to screen hundreds of patients with this condition and see if they are more likely to develop a greater disease than before," Kang added.

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